Volume : II, Issue : X, November - 2012 SPECTROSCOPIC AND BIOLOGICAL STUDIES OF SOME NEW COORDINATION COMPOUNDS OF TIN (II) AND (IV) WITH SEMICARBAZONES AND THIOSEMICARBAZONES.JITENDRA KUMAR RAWAT , HARI SHANKAR YADAV , A.K. VARSHNEY AND S. VARSHNEY Published By : Laxmi Book Publication Abstract : The present paper is a report on the synthesis of some new tin (II) and tin (IV)
complexes by the reaction of stannous chloride and dimethyltin dichloride with
semicarbazones and thiosemicarbazones using tetrahydrofuran(THF) as reaction
medium. Semicarbazones and thiosemicarbazones used in these studies are synthesized
by the condensation of 1-acetyl-2-naphthol, 2-acetyl-1-naphathol, 2-acetyl-5-methyl
furan, 2-acetyl-4-methyl thiophene and 2-acetyl-naphthalene with semicarbazide/
thiosemicarbazide. The bonding pattern and geometry of tin complexes are
characterized by spectroscopic evidences. The ligands and their metal complexes have
been screened for antitubercular, antibacterial and antifungal activities and are found
quite active in this respect. Plant growth activity has also been evaluated and is found
negative growth. Keywords : Article : Cite This Article : JITENDRA KUMAR RAWAT , HARI SHANKAR YADAV , A.K. VARSHNEY AND S. VARSHNEY, (2012). SPECTROSCOPIC AND BIOLOGICAL STUDIES OF SOME NEW COORDINATION COMPOUNDS OF TIN (II) AND (IV) WITH SEMICARBAZONES AND THIOSEMICARBAZONES.. Indian Streams Research Journal, Vol. II, Issue. X, http://oldisrj.lbp.world/UploadedData/1614.pdf References : - F.R. Pavan, P.I.daS. Maia, S.R.A. Leite, V.M. Deflon, A.A. Batista, D.N. Sato, S.G. Franzblau and C.O.F. Leite,Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide / hydrazones: Anti- Mycobacterium tuberculosis activity and cytotoxicity Eur. J. Med. Chem., 45, 1898-1905 (2010).
- S.Chandra and L.K. Gupta Spectroscopic evaluation of manganese (II) complexes derived from semicarbazones and thiosemicarbazones, Spectrochim.Acta, 6L, 2549-2554 (2005).
- M.J.M. Campbell, B. Beecroft and R. Grzeskowiak,Complexes of semicarbazones and thiosemicarbazones with nickel (II). J. Inorg. Nucl. Chem., 36 (1), 55-59 (1974).
- R.N. Prabhu, D. Pandiarajan and R. Ramesh,Ruthenium (II) mediated C-H activation of substituted acetophenone thiosemicarbazones: Synthesis, structural characterization, luminescence and electrochemical properties. J. Organometal. Chem., 694 (26), 4170-4177 (2009).
- S.N. Sengupta, O.P. Pandey, B.K. Srivastava and V.K. Sharma,Synthesis, structural and biochemical aspects of titanocene zirconocene chelates of acetylferrocenyl thiosemicarbazones. Trans. Met. Chem., 23 (4), 349-353 (1998).
- R.B.de Oliveira, E.M.de Souza-Fagundes, R.P.P. Soares, A.A. Andrade, A.U. Krettli and C.L. Zani, Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivative. Eur. J. Med. Chem., 43 (9), 1983-1988 (2008).
- T.R. Todorovic, A. Bacchi, N.O. Juranic, D.M. Sladic, G. Pelizzi, T.T. Bozic, N.R. Filipovic and K.K. Andelkovic,Synthesis and characterization of novel Cd (II), Zn (II) and Ni (II) complexes with 2-quinoline carboxaldehyde selenosemicarbazone crystal structure of bis (2-quinoline carboxaldehyde selenosemicarbazonato) nickel (II). Polyhedron, 26 (13), 3428-3436 (2007)
- D.X. West, J.K. Swearingen, J.V.-Martinez, S.H.-Ortego, A.K. El-Sawaf, F. Meurs, A. Castineiras, I. Garcia and E. Bermejo, Spectral and structural studies of iron (III), cobalt (II, III) and nickel (II) complexes of 2- pyridine formamide N (4)-methylthiosemicarbazone. Polyhedron, 18 (22), 2919-2929 (1999).
- Structural and spectral characterization of transition metal complexes of 2-pyridine formamide N (4)- dimethylthiosemicarbazone. Polyhedron, 22 (1), 83-92 (2003).
- A.K. Varshney and J.P. Tandon Organotin (IV) complexes of semicarbazone and thiosemicarbazone of heterocyclic aldehyde. Egypt. J. Chem., 32, 110-114 (1989).
- C.C. Gatto, E.S. Lang, A. Jagst and U. Abram,Dioxouranium (VI) complexes with 2, 6-acetylpyridinebenzoylhydrazones and thiosemicarbazones Inorg. Chim. Acta, 357, 4405 (2004).
- K.H. Reddy, P.S. Reddy and P.R. Babu, Synthesis, spectral studies and nuclease activity of mixed ligand copper (II) complexes of heteroatomic semicarbazones/ thiosemicarbazones and pyridine. J. Inorg. Biochem, 77, 169 (1999).
- S. Chandra and L. K. Gupta, Spectroscopic and biological studies on newly synthesized nickel (II) complexes of semicarbazones and thiosemicarbazones. Spectrochim. Acta, 62, 1089 (2005).
- J.S. Casas, M.S. G.-Tasende and J. Sordo,Main group metal complexes of semicarbazones and thiosemicarbazones. A structural review. Coord.Chem.Rev., 209, 197 (2000).
- S. Padhye and G.B. Kauffman,Transition metal complexes of semicarbazones and thiosemicarbazones. Coord. Chem. Rev., 63, 127 (1985).
- Rekha Sangtyani, Vinay Kumar, R.C.Meena, A K Varshney and S Varshney. Cyclic Volyammetric reduction of 2- Acetylpyridine semicarbazone at Glassy Carbon Electrode.Int.J.Chem.Rese.01, 180- 184(2012)
- R. Kavya and J.S. Samuel3-Chloro-2-methylphenyl-substituted semicarbazones: Synthesis and anticonvulsant activity, J. Stables and D. Sriram, Eur. J. Med.Chem. 39,729 (2004).
- N.C. Kasuga, K. Onodera, S. Nakano, K. Hayashi and K. Nomiya, Synthesis, crystal structures and antimicrobial activities of 6-coordinate antimony (III) complexes with tridentate 2- acetylpyridine thiosemicarbazone, bis (thiosemicarbazone) and semicarbazone ligands. J. Inorg. Biochem., 100, 1176 (2006)
- I.C. Mendes, L.M. Botion, A.V.M. Ferreira, E.E. Castellano and H. Beraldo, Vanadium complexes with 2-pyridineformamide thiosemicarbazones: In vitro studies of insulin-like activity. Inorg. Chim. Acta, 362, 414 (2009).
- M.S. Singh and P.K. Singh,Highly versatile synthesis of some organotin (IV) complexes of 2- hydroxyacetophenone semicarbazone and thiosemicarbazone. Synth. React. Inorg. Met.-Org. and Nano- Met.Chem., 33, 1895 (2003).
- H.L. Singh, M. Sharma and A.K. Varshney, Synthesis and characterization of some tin (II) complexes with semicarbazones and thiosemicarbazones of heterocyclic ketones., Synth. React. Inorg. Met.-Org. and Nano-Met. Chem., 29, 817 (1999).
- S. Chandra and M. Tyagi,Synthesis, structural and antibacterial studies of some transition metal complexes derived from thiosemicarbazone and semicarbazone. Phosphorus, Sulfur and Silicon, 184, 778 (2009).
- N.C. Kasuga, K. Sekino, M. Ishikawa, A. Honda, M. Yokoyama, S. Nakano, N. Shimada, C. Koumo and K. Nomiya, Synthesis, structural characterization and antimicrobial activities of 12 zinc (II) complexes with four thiosemicarbazone and two semicarbazone ligands. J. Inorg. Biochem., 96, 298 (2003)
- Amany L. Kansoh, E.A.M. Youssef, M.A. Abd-El-Ghaffar, Studies on the antifungal activities of the novel synthesized chelating co-polymer emulsion lattices and their silver complexes. Biotechnol. Agron. Soc. Environ. 12(3), 231-238 2008
- M. Nath, N. Sharma and C.L. Sharma,Studies on some organotin (IV) complexes of semicarbazones and thiosemicarbazones. Synth. React. Inorg. Met.-Org. and Nano-Met. Chem., 19, 339 (1989).
- Arpita Verma, Shilpa Sharma, Monica Bedi, S.Varshney and A.K.Varshney* Structural characterization and antimicrobial studies of some new coordination compound of tin (II) and tin (IV) with semicarbazones and thiosemicarbazones. Int.J.Chem.Sci. 9(1), 123-130(2011)
- A. Saxena and J.P. Tandon Antitumor activity of some diorganotin and tin (IV) complexes of Schiff bases. Cancer Letters, 19, 73 (1983).
- A.E. Graminha, C. Rodrigues, A.A. Batista, L.R. Teixeira, E.S. Fagundes, H. Beraldo, Ruthenium (II) complexes of 2- benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines. Spectrochim. Acta, 69, 1073 (2008).
- A.E. Liberta, D.X. West, Structures of nickel (II) and copper (II) complexes of 2- acetylpyridine azacyclothiosemicarbazones. Bio Metals, 5, 121 (1992).
- Rajeev Soni, Jeremy P.Carmichael , lTZahid H.Shah, A.A ns Jame s,H. Murray, A Family of Cyclin D Homologs from plants differentially controlled by growth regulators and containing the conserved retinoblastoma protein interaction motif. Amer. Soci. of Plant Phys. 7, 85-103, (1995)
- D. praehensilis Bernard Malaurie, Okito Pungu 2 & Marie - France Trouslot Effect o f growth regulators conc ent rat ions on morphologi cal development of meristemtips in Dioscorea cayenensis-D, rotundata c omp l e x and. Plant Cell and Organ Cult. 41: 229-235, (1995).
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