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Volume : I, Issue : VI, July - 2011

Serum Interleukin-18 levels at a base line could serve as a better differentiating factor for carcinoma prostate and benign prostate hyperplasia –A study in north Indian population

S Dwivedi , S Singh , V Gupta , A Goel , S M Natu , S Khattri

Published By : Laxmi Book Publication

Abstract :

Aim: To explore the role of serum interleukin -18 (IL-18) levels and its significance in prostate carcinoma patients. Method: 90 subjects were enrolled during June 2010 to May 2011 after Institutional ethical approval, 44 biopsy proven prostate cancer patients and age matched independent 46 benign prostate hyperplasia (BPH) patients as controls with in age group of 40-80 years. The Serum PSA level, interleukin-18 levels were measured by enzyme linked immunosorbent assay (ELISA) and significance of difference between various group was compared by using ANOVA analysis. Results The mean IL-18 of carcinoma prostate group was found to be significantly (p<0.01) higher than BPH group. It also showed its increase value in patient with its advanced stages.

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Cite This Article :

S Dwivedi , S Singh , V Gupta , A Goel , S M Natu , S Khattri, (2011). Serum Interleukin-18 levels at a base line could serve as a better differentiating factor for carcinoma prostate and benign prostate hyperplasia –A study in north Indian population. Indian Streams Research Journal, Vol. I, Issue. VI, http://oldisrj.lbp.world/UploadedData/334.pdf

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